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Upadacitinib-<sup>15</sup>N,d<sub>2</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W727879
    Upadacitinib-15N,d2

    ABT-494-<sup>15sup>N,d<sub>2sub>

    		 Isotope-Labeled Compounds Others
    Upadacitinib- 15N,d2 (ABT-494- 15N,d2) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- 15N,d2 (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib- 15N,d2 (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- 15N,d2 (ABT-494) can be used for several autoimmune disorders research .
    Upadacitinib-15N,d2

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